Operational excellence and continuous improvement leader with deep experience optimizing complex healthcare operations — bridging Lean methodology, data analytics, and change management to drive measurable outcomes across academic medical centers, global health systems, and enterprise healthcare organizations.
Yigu Chen grew up in Shanghai and came to public health through a somewhat indirect path — one shaped by equal parts curiosity, practicality, and a persistent interest in why organizations that are supposed to help people sometimes make it harder than it needs to be.
He holds an MPH from Boston University School of Public Health (GPA 3.9, Delta Omega, Epsilon Phi Delta) and is certified as a Six Sigma Black Belt and Project Management Professional — credentials he thinks of less as achievements and more as a shared language for working across clinical, operational, and administrative teams.
Over the past decade, he has had the good fortune to work alongside talented colleagues at Beth Israel Deaconess Medical Center, where he also taught at Harvard Medical School, at Memorial Sloan Kettering Cancer Center, and at GE Healthcare across hospitals in Greater China. Each role has taught him something different about what change actually requires — and how rarely it follows a straight line.
He has contributed to 35+ publications on quality systems, patient safety, and clinical operations, and finds the research process valuable less for the publications themselves and more for what it demands: rigor, patience, and a willingness to be wrong.
These days he works independently, helping healthcare organizations think through operational problems — always trying to be useful without overstating what any one person or framework can accomplish.
Work History
Aug 2024 – Present
Independent Advisor
Healthcare Improvement Consultant
Jul 2022 – Jul 2024
GE Healthcare Greater China
Lean Leader, Lean Healthcare Solutions
Nov 2020 – May 2022
Memorial Sloan Kettering Cancer Center New York City
Senior Process Improvement Engineer, Operational Excellence
Sep 2014 – Oct 2020
Beth Israel Deaconess Medical Center Boston
Lead, Quality & Process Improvement
2018 – 2020
Harvard Medical School Boston
Faculty, Principal Associate (Joint Academic Appointment)
Education
Certifications
| # | Title | Year | Category |
|---|---|---|---|
| 01 | Using the Model for Improvement and Plan-Do-Study-Act to Effect SMART Change and Advance Quality Cancer Cytopathology 129 (1), 9–14 | 2021 | QI Methodology & Education |
| 02 | Process Mapping: A Cornerstone of Quality Improvement Cancer Cytopathology 125 (12), 887–890 | 2017 | QI Methodology & Education |
| 03 | Results from the 2019 ASC Survey on Rapid On-Site Evaluation — Part 1: Objective Practice Patterns Journal of the American Society of Cytopathology 8 (6), 333–341 | 2019 | Research Analytics |
| 04 | Visceral Pleural Invasion in Pulmonary Adenocarcinoma: Differences in CT Patterns Between Solid and Subsolid Cancers Radiology: Cardiothoracic Imaging 1 (3), e190071 | 2019 | Research Analytics |
| 05 | Molecular Testing Turnaround Time for Non–Small Cell Lung Cancer Confirms Feasibility of CAP/IASLC/AMP Guideline Recommendations Clinical Lung Cancer 18 (5), e349–e356 | 2017 | Healthcare Operations |
| 06 | Pre-Analytic Error: A Significant Patient Safety Risk Cancer Cytopathology 126, 738–744 | 2018 | Patient Safety |
| 07 | Measuring and Assuring Quality Performance in Cytology: A Toolkit Cancer Cytopathology 125 (S6), 502–507 | 2017 | QI Methodology & Education |
| 08 | Measurement Bias of Gross Pathologic vs. Radiologic Tumor Size of Resected Lung Adenocarcinomas: Implications for T-Stage Revisions American Journal of Clinical Pathology 147 (6), 641–648 | 2017 | Research Analytics |
| 09 | Frozen-Section Checklist Implementation Improves Quality and Patient Safety American Journal of Clinical Pathology 151 (6), 607–612 | 2019 | Healthcare Operations |
| 10 | Results from the 2019 ASC Survey on Rapid Onsite Evaluation (ROSE) — Part 2: Subjective Views Among the Cytopathology Community Journal of the American Society of Cytopathology 9 (6), 570–578 | 2020 | Research Analytics |
| 11 | Preoperative Bronchial Cytology for the Assessment of Tumor Spread Through Air Spaces in Lung Adenocarcinoma Resection Specimens Cancer Cytopathology 128 (4), 278–286 | 2020 | Research Analytics |
| 12 | Comparison of Plasma-Thrombin, HistoGel, and CellGel Cell Block Preparation Methods with Paired ThinPrep Slides in Mediastinal Granulomatous Disease Journal of the American Society of Cytopathology 8 (2), 52–60 | 2019 | Research Analytics |
| 13 | Molecular Testing Turnaround Time for Non-Small-Cell Lung Cancer: Monitoring a Moving Target Clinical Lung Cancer 19 (5), e589–e590 | 2018 | Healthcare Operations |
| 14 | Achieving High Reliability in Histology: An Improvement Series to Reduce Errors American Journal of Clinical Pathology 146 (5), 554–560 | 2016 | Healthcare Operations |
| 15 | Pathologic T Descriptor of Nonmucinous Lung Adenocarcinomas Now Based on Invasive Tumor Size: How Should Pathologists Measure Invasion? American Journal of Clinical Pathology 150 (6), 499–506 | 2018 | Research Analytics |
| 16 | False-Negative Urine Human Chorionic Gonadotropin Testing in the Clinical Laboratory Laboratory Medicine 51 (1), 86–93 | 2020 | Research Analytics |
| 17 | Optimizing Unilateral Deep Inferior Epigastric Perforator Flap Breast Reconstruction: A Quality Improvement Study The Journal for Healthcare Quality (JHQ) 44 (6), 354 | 2022 | Healthcare Operations |
| 18 | Towards High Reliability in National Pathology Education: Evaluating the USCAP Educational Product Academic Pathology 9 (1), 100048 | 2022 | QI Methodology & Education |
| 19 | Pathology Trainees Rarely Report Safety Incidents: A Review of 13,722 Safety Reports and a Call to Action Academic Pathology 9 (1), 100049 | 2022 | Patient Safety |
| 20 | Assessing Inpatient Platelet Ordering Practice: Evaluation of Computer Provider Order Entry Overrides Vox Sanguinis 116 (6), 702–712 | 2021 | Healthcare Operations |
| 21 | Impact of a Modified HistoGel Method for Processing Endocervical Curettage Specimens on Diagnostic Yield American Journal of Clinical Pathology 155 (1), 141–147 | 2021 | Research Analytics |
| 22 | What Can We Learn from No-Harm Events and Near Misses in Pathology? A Review of 244 Cases Laboratory Investigation 98, 769–770 | 2018 | Patient Safety |
| 23 | The Next Phase in Patient Safety Education: Towards a Standardized, Tools-Based Pathology Patient Safety Curriculum Academic Pathology 10 (2), 100081 | 2023 | QI Methodology & Education |
| 24 | Adopting the Quality Dashboard in Pathology: Real-Time Data Monitoring and Improvement Laboratory Investigation 96, 492A–492A | 2016 | QI Methodology & Education |
| 25 | Diagnostic Error, Interlaboratory Communication, and Resource Management in Cytopathology–Surgical Pathology Collaboration Cancer Cytopathology 131 (2), 75–77 | 2023 | Patient Safety |
| 26 | Optimizing Unilateral DIEP Flap Breast Reconstruction Leads to Decreased Hospitalization Time: A Quality Improvement Study Plastic and Reconstructive Surgery–Global Open 10 (4S), 92–93 | 2022 | Healthcare Operations |
| 27 | Impact of a Cellular Concentration Method on Endocervical Curettage Specimen Adequacy Laboratory Investigation 100 (SUPPL 1), 1892–1893 | 2020 | Research Analytics |
| 28 | Cytology Specimen Contamination Leads to a False-Positive Surgical Pathology Diagnosis: Root Cause Analysis and Patient Safety Lessons Cancer Cytopathology 127 (10), 618–620 | 2019 | Patient Safety |
| 29 | Quality Assessment and Improvement of USCAP Annual Meeting Educational Offerings Laboratory Investigation 99 | 2019 | QI Methodology & Education |
| 30 | False Positive Diagnosis of Lymph Node Metastases in a 34-Year-Old Woman with Extraskeletal Myxoid Chondrosarcoma: A Root Cause Analysis Cancer Cytopathology | 2018 | Patient Safety |
| 31 | Comparison of Plasma-Thrombin, HistoGel, and CellGel Cell Block Preparation Methods in Mediastinal Granulomatous Disease Journal of the American Society of Cytopathology 7 (5), S6–S7 | 2018 | Research Analytics |
| 32 | Do Pathology Trainees Report Fewer Incidents Than Their Peers? A Review of 13,722 Incidents Laboratory Investigation 98, 769–769 | 2018 | Patient Safety |
| 33 | Checklist Implementation for Intraoperative Consultations: Improved Quality and Safety Laboratory Investigation 97, 501A–502A | 2017 | Healthcare Operations |
| 34 | Blood Bank STAT Turnaround Time: Tracking Our Steps, Improving Our Processes Transfusion 56 (S4), 3A–275A | 2016 | Healthcare Operations |
| 35 | Pathology M&M Rounds: A Focus on Transparency and Process Improvement Laboratory Investigation 96, 492A–492A | 2016 | QI Methodology & Education |





































